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1.
J. venom. anim. toxins incl. trop. dis ; 28: e20220020, 2022. tab
Article in English | LILACS, VETINDEX | ID: biblio-1405508

ABSTRACT

Peripheral facial paralysis (PFP) has been shown to be a neurological manifestation of COVID-19. The current study presents two cases of PFP after COVID-19, along with a rapid review of known cases in the literature. Both case reports were conducted following CARE guidelines. We also performed a systematic review of PFP cases temporally related to COVID-19 using PubMed, Embase, and Cochrane Library databases on August 30, 2021, using a rapid review methodology. The two patients experienced PFP 102 and 110 days after COVID-19 symptom onset. SARS-CoV-2 RNA was detected in nasal samples through reverse-transcription real-time polymerase chain reaction (RT-qPCR) testing. Anosmia was the only other neurological manifestation. PFP was treated with steroids in both cases, with complete subsequent recovery. In the rapid review, we identified 764 articles and included 43 studies. From those, 128 patients with PFP were analyzed, of whom 42.1% (54/128) were male, 39.06% (50/128) female, and in 23 cases the gender was not reported. The age range was 18 to 59 (54.68%). The median time between COVID-19 and PFP was three days (ranging from the first symptom of COVID-19 to 40 days after the acute phase of infection). Late PFP associated with COVID-19 presents mild symptoms and improves with time, with no identified predictors. Late PFP should be added to the spectrum of neurological manifestations associated with the long-term effects of SARS-CoV-2 infection as a post COVID-19 condition.


Subject(s)
Humans , Facial Paralysis/etiology , COVID-19/complications , Neuromuscular Diseases/etiology
2.
Online braz. j. nurs. (Online) ; 17(2)jun. 2018.
Article in English, Spanish, Portuguese | BDENF, LILACS | ID: biblio-1118040

ABSTRACT

OBJETIVO: compreender o processo de resiliência de mulheres que tiveram o parto domiciliar planejado transferido para o hospital. MÉTODO: trata-se de um estudo do tipo exploratório de abordagem qualitativa, realizado com dez mulheres que planejaram o parto domiciliar, mas que por algum motivo tiveram que ser transferidas para o hospital. A coleta de dados foi realizada mediante entrevistas semiestruturadas, analisadas pela análise de conteúdo do tipo temática. RESULTADOS: constatou-se que todas as entrevistadas vivenciaram o trauma devido à transferência hospitalar, mas apenas uma chegou até a etapa final do processo de resiliência, a adaptação. CONCLUSÃO: a participação da enfermeira obstetra nesse processo é fundamental, visto que poderá auxiliar essa mulher a encontrar fatores que possam desenvolver o processo de resiliência, mediante diálogo, compreensão, abertura e acolhimento. Isso possibilitará compreender o outro na sua totalidade, e captar suas dores e inseguranças por meio de uma relação humanizada.


AIM: understand the resilience process of women who had the planned home birth transferred to the hospital. METHOD: this is an exploratory study that uses a qualitative approach performed with ten women who planned home birth, but who, for some reason, had to be transferred to the hospital. The data collection was performed through semi-structured interviews, analyzed by content analysis of the thematic type. RESULTS: it was found that all the interviewees experienced the trauma due to the hospital transfer, but only one reached the final stage of the resilience process, the adaptation. CONCLUSION: the participation of obstetrical nurses in this process is fundamental, since it can help these women to find factors that can develop the process of resilience through dialogue, understanding, openness and acceptance. This will make it possible to understand the other in its totality, and to capture their pains and insecurities through a humanized relationship.


OBJETIVO: comprender el proceso de resiliencia de las mujeres que tuvieron el parto domiciliario planificado transferido para el hospital. MÉTODO: se trata de un estudio de tipo exploratorio de abordaje cualitativo, realizado con diez mujeres que planificaron el parto domiciliario, pero que por algún motivo tuvieron que ser transferidas al hospital. La recolección de los datos se realizó mediante entrevistas semiestructuradas, analizadas por el análisis de contenido de tipo temático. RESULTADOS: se constató que todas las entrevistadas experimentaron un trauma causado por la transferencia hospitalaria, pero solo una llegó hasta la etapa final del proceso de resiliencia, la adaptación. CONCLUSIÓN: la participación de la enfermera obstetra en ese proceso es fundamental, ya que podrá auxiliar a esta mujer a encontrar factores que desarrollen su proceso de resiliencia, mediante el diálogo, comprensión, abertura y la acogida. Eso posibilitará comprender al otro en su totalidad, y captar sus dolores e inseguridad a través de una relación humanizada.


Subject(s)
Humans , Female , Pregnancy , Adult , Women's Health , Resilience, Psychological , Home Childbirth/psychology , Humanizing Delivery , Obstetric Nursing
3.
Braz. j. microbiol ; 48(1): 13-24, Jan.-Mar. 2017. tab, graf
Article in English | LILACS | ID: biblio-839339

ABSTRACT

Abstract Specific proteases capable of degrading native triple helical or denatured collagen have been required for many years and have a large spectrum of applications. There are few complete reports that fully uncover production, characterization and purification of fungi collagenases. In this review, authors searched through four scientific on line data bases using the following keywords (collagenolytic OR collagenase) AND (fungi OR fungus OR fungal) AND (production OR synthesis OR synthesize) AND (characterization). Scientific criteria were adopted in this review to classify found articles by score (from 0 to 10). After exclusion criteria, 21 articles were selected. None obtained the maximum of 10 points defined by the methodology, which indicates a deficiency in studies dealing simultaneously with production, characterization and purification of collagenase by fungi. Among microorganisms studied the non-pathogenic fungi Penicillium aurantiogriseum and Rhizoctonia solani stood out in volumetric and specific collagenase activity. The only article found that made sequencing of a true collagenase showed 100% homology with several metalloproteinases fungi. A clear gap in literature about collagenase production by fungi was verified, which prevents further development in the area and increases the need for further studies, particularly full characterization of fungal collagenases with high specificity to collagen.


Subject(s)
Collagen/metabolism , Collagenases/metabolism , Fungi/metabolism , Substrate Specificity , Collagen/chemistry , Collagenases/isolation & purification , Collagenases/biosynthesis , Collagenases/chemistry , Culture Media , Enzyme Activation , Proteolysis , Fungi/classification
4.
Rio de Janeiro; s.n; 2013. 83 p. ilus, mapas, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-711370

ABSTRACT

Introdução: A asma em Itaboraí, RJ tem sido um problema de saúde pública ao longo dos anos, devido as suas altas taxas de internação pela doença. Atualmente, o município está sofrendo a construção do COMPERJ – Complexo Petroquímico do Estado do Rio de Janeiro, que inevitavelmente causará impactos na exposição a poluentes atmosféricos, fator determinante para fisiopatologia da asma. Conhecer a situação dos sintomas de asma nomunicípio possibilita subsídios para gestão pública para a tomada de decisão e implantação de ações em saúde e ambiente.Objetivo: Analisar a prevalência e a gravidade dos sintomas da asma no município de Itaboraí, segundo sexo e escola, analisando a distribuição geográfica dos sintomas e se os estudantes sintomáticos estão concentrados em área com maior potencial de emissão de poluentes atmosféricos no município de Itaboraí, Rio de Janeiro;Metodologia: Estudo descritivo da prevalência de asma em adolescentes de 13 a 14 anosno município de Itaboraí/Rio de Janeiro/Brasil. Foram analisados 2116 questionários referentes à aplicação dos questionários ISAAC nas escolas, realizada pela Secretaria Municipal de Saúde de Itaboraí. As escolas foram divididas em 3 clusters de acordo com o número de questionários pela ferramenta Moran Local I do software ARCGIS. Foram analisados os clusters segundo sintomas respiratórios e fontes de emissão de poluentes atmosféricos, a saber: quantidade de indústrias de cerâmica, densidade de vias e densidade de pavimentação, por meio da confecção de mapa multicritério. Resultados: O município de Itaboraí apresentou prevalência de asma de 17,8% e gravidade de 5,7%. Sendo a maior prevalência e gravidade encontradas no cluster 1, onde também há maior quantidade de habitantes e maior concentração de fontes de emissão de poluentes atmosféricos. Conclusão: Conclui-se, a partir deste estudo, que os bairros de Itaboraí (Centro), Outeiro das Pedras, Rio Várzea, Ampliação, Quissamã, Jardim Imperial, Nova Cidade, Areal e Santo Expedito – no distrito de Itaboraí, os bairros de Porto das Caixas e João Caetano –nos distritos de Porto das Caixas e Itambi respectivamente, assim como os bairros de Aldeia da Prata, Apolo II, Vila Brasil, Novo Horizonte, Monte Verde e Santo Antônio – no distrito de Manilha, caracterizam-se como área crítica para o desenvolvimento dos sintomas da asma. Portanto, esta região, que compõe o cluster 1, deve ser a área prioritária no município de Itaboraí para o desenvolvimento das ações de prevenção e controle da asma na cidade.


Introduction: Asthma in Itaboraí / RJ has been a public health problem over the years, due to their high rates of hospitalization for the disease. Currently, the county is undergoing construction COMPERJ - Petrochemical Complex of the State of Rio de Janeiro, which will cause inevitably impacts on exposure to air pollutants, determining factor in the pathophysiology of asthma. Knowing the situation of asthma symptoms in the municipality provides subsidies for public management for decision making and implementation of actions on health and environment. Objective: To assess the prevalence and severity of asthma symptoms in Itaboraí by gender and school, analyzing the geographical distribution of symptoms and if the symptomatic students are concentrated in areas with the greatest potential for emission of air pollutants in Itaboraí, Rio de Janeiro. Methodology: A descriptive study of the prevalence of asthma in adolescents aged 13 to 14 years in Itaboraí / Rio de Janeiro / Brazil. 2116 questionnaires were analyzed regarding the application of ISAAC questionnaires in schools, conducted by the Municipal Health of Itaboraí. The schools were divided into three clusters according to the number of questionnaires by the tool Moran Local I, ARCGIS ® software. We analyzed the clusters second respiratory symptoms and sources of atmospheric pollutants, namely quantity of ceramic industries, density and density paving roads, by making multicriteria map. Results: The Itaboraí presented asthma prevalence of 17.8% and severity of 5.7%. Being the highest prevalence and severity found in cluster 1, where also there are more people and and higher concentration of emission sources of air pollutants. Conclusion: It is concluded from this study that the neighborhoods Itaboraí (Centro), Outeiro das Pedras, Rio Varzea, Ampliação, Quissamã, Jardim Imperial, Nova Cidade, Areal e Santo Expedito - District Itaborai, neighborhoods Porto das Caixas e João Caetano - in the districts of Porto das Caixas and Itambi respectively, as well as the neighborhoods of Aldeia da Prata, Apolo II, Vila Brasil, Novo Horizonte, Monte Verde e Santo Antonio - in the district of Manilha, characterized as critical area for the development of asthma symptoms. Therefore, this region, which makes up the cluster 1, should be the priority area in Itaboraí for the development of prevention and control of asthma in the city.


Subject(s)
Humans , Adolescent , Adolescent Health , Air Pollution , Asthma , Inhalation Exposure , Severity of Illness Index , Ceramic Industry/adverse effects , Prevalence
5.
Rev. Soc. Bras. Clín. Méd ; 8(4)jul.-ago. 2010.
Article in Portuguese | LILACS | ID: lil-555454

ABSTRACT

JUSTIFICATIVA E OBJETIVOS: A importância deste estudo se deve ao fato da escassez em relação aos valores percentuais de prevalência das comorbidades do diabetes na literatura nacional. Desta forma, o objetivo foi caracterizar os pacientes diabéticos cadastrados e identificar suas comorbidades, visando comparar os dados com a realidade estadual e nacional. MÉTODO: Trata-se de um estudo epidemiológico descritivo, obtido através dos prontuários de 69 pacientes diabéticos cadastrados no Programa Hiperdia na Área 11 do Programa de Saúde da Família da Vila Davi no município de Bragança Paulista. RESULTADOS: Os dados obtidos dos 69 prontuários avaliados apontaram 75% dos pacientes eram do sexo feminino, 71% com idade igual ou superior a 46 anos, 30% apresentaram sobrepeso ou obesidade. As comorbidades identificadas foram 13% de pacientes com retinopatia, 10% com pé diabético e 11,5% com nefropatia. CONCLUSÃO: Os dados obtidos condizem com os dados da literatura estadual e nacional quanto às incidências das comorbidades relacionadas ao diabetes. O estudo permitiu identificar deficiências nas informações disponíveis nos prontuários dos pacientes diabéticos.


BACKGROUND AND OBJECTIVES: The survey's importance is due to the lack of percentage values in prevalence of the diabetes comorbidities in national data. Therefore the objective of this study is to characterize the diabetic patients registered to identify their comorbidities to compare with state and national reality data. METHOD: Study epidemiological research of the type descriptive about 69 diabetic's patient records registered in Hiperdia Program of the 11th Area at Vila Davi Family Health Program in Bragança Paulista city. RESULTS: The data provided from the 69 patient records showed: 75% of the patients were women, 71% were 46 years or older, 30% presented overweight or obesity. The comorbidities in the patient records were: retinopathy in 13%, diabetic feet in 10% and nephropathy in 11.5%. CONCLUSION: The data obtained from the survey match the state and national data when compared to the occurrence of diabetes comorbidities. The study identified deficiencies in the data available of diabeticïs patient records of the Hiperdia Program.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged, 80 and over , Comorbidity , Diabetes Mellitus , National Health Strategies
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